Tumours in white suckers from Lake Michigan tributaries: pathology and prevalence

TitleTumours in white suckers from Lake Michigan tributaries: pathology and prevalence
Publication TypeJournal Article
Year of Publication2017
AuthorsBlazer, V. S., Walsh H. L., Braham R. P., Hahn C. M., Mazik P., and McIntyre P. B.
JournalJournal of Fish Diseases
Volume40
Issue3
Number of Pages377-393
Date PublishedMar
Type of ArticleArticle
Reprint Number0140-7775
LTER Accession NumberWOS:000394840500008
Keywordscatostomus-commersoni; great-lakes; brown bullhead; rainbow-trout;, developmental-stages; bullhead ameiurus-nebulosus; waste-water effluent;, environmental health; liver neoplasms; skin neoplasms; tumours; White, Fisheries; Marine & Freshwater Biology; Veterinary Sciences, reproductive disruption, sucker, zebrafish danio-rerio; roach rutilus-rutilus; different
Abstract

The prevalence and histopathology of neoplastic lesions were assessed in white sucker Catostomus commersonii captured at two Lake Michigan Areas of Concern (AOCs), the Sheboygan River and Milwaukee Estuary. Findings were compared to those observed at two non-AOC sites, the Root and Kewaunee rivers. At each site, approximately 200 adult suckers were collected during their spawning migration. Raised skin lesions were observed at all sites and included discrete white spots, mucoid plaques on the body surface and fins and large papillomatous lesions on lips and body. Microscopically, hyperplasia, papilloma and squamous cell carcinoma were documented. Liver neoplasms were also observed at all sites and included both hepatocellular and biliary tumours. Based on land use, the Kewaunee River was the site least impacted by human activities previously associated with fish tumours and had significantly fewer liver neoplasms when compared to the other sites. The proportion of white suckers with liver tumours followed the same patterns as the proportion of urban land use in the watershed: the Milwaukee Estuary had the highest prevalence, followed by the Root, Sheboygan and Kewaunee rivers. The overall skin neoplasm (papilloma and carcinoma) prevalence did not follow the same pattern, although the percentage of white suckers with squamous cell carcinoma exhibited a similar relationship to land use. Testicular tumours (seminoma) were observed at both AOC sites but not at the non-AOC sites. Both skin and liver tumours were significantly and positively associated with age but not sex.

URL<Go to ISI>://WOS:000394840500008
Print Copy LocationJ. Fish Dis.